COMPARATIVE-STUDIES ON DATA-COLLECTION AND DATA TREATMENT IN KINETIC-BASED DETERMINATIONS WITH 2 ROTATING BIOREACTOR AMPEROMETRIC DETECTIONSYSTEMS

Two cell configurations involving a rotating bioreactor and a stationa ry platinum-ring amperometric detector are compared with regard to dat a produced by continuous-flow and continuous-flow/stopped-flow/continu ous-flow operations. In addition to data collection, six kinetic-based approaches to data treatment are also compared. The approaches to dat a treatment considered here are: (1) the initial rate measurement, (2) integration of the signal time profile, (3) a linear steady-state pre dictive approach, (4) a nonlinear steady-state predictive approach, (5 ) a single measurement fixed-time mode, and (6) a multimeasurement fix ed-time mode.