Postoperative fatigue (POF) appears to be less following laparoscopic
surgery but this has not been proven previously. This study compared a
group of patients who had undergone open cholecystectomy with a group
undergoing laparoscopic cholecystectomy. Postoperative fatigue was fo
und to be decreased in duration in the patients having laparoscopic su
rgery, returning to pre-operative fatigue levels by 14 days, compared
to 28 days for open surgery. Postoperative pain in the first 24h and t
he early metabolic response to surgery were similar for both groups. T
he authors conclude that laparoscopic surgery is associated with decre
ased POF and that this is unlikely to be accounted for by a decrease i
n the early metabolic response to surgery.