ELECTROSPRAY MASS-SPECTROMETRY OF PENTACOSA-SACCHARIDES OF BLOOD-GROUP I - ACTIVITY AND RELATED-COMPOUNDS

Citation
T. Ii et al., ELECTROSPRAY MASS-SPECTROMETRY OF PENTACOSA-SACCHARIDES OF BLOOD-GROUP I - ACTIVITY AND RELATED-COMPOUNDS, Organic mass spectrometry, 28(11), 1993, pp. 1340-1344
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear",Spectroscopy
Journal title
ISSN journal
0030493X
Volume
28
Issue
11
Year of publication
1993
Pages
1340 - 1344
Database
ISI
SICI code
0030-493X(1993)28:11<1340:EMOPOB>2.0.ZU;2-C
Abstract
The structural characterization of large synthetic oligosaccharides an d related glycoconjugates performed by the use of electrospray ionizat ion mass spectrometry (ESIMS) is described. The largest molecules desc ribed here are unprotected and protected pentaantennary pentacosasacch arides 2 and 5 with average molecular masses of 4441 and 9416, respect ively. The straight-chain neutral ceramide decasaccharide (d18:1/c24:0 ) 6 and the disialoganglioside GD2 (d18:1/c24:0) 7 were also successfu lly analyzed by ESIMS. In addition to exact mass determination, collis ion-induced dissociation (CID) spectrometry of these compounds provide d saccharide chain sequence information.