PRENATAL CONFIRMATION OF TRISOMY-12 MOSAICISM BY FETAL SKIN BIOPSY

Authors
CARTOLANO R GUERNERI S FOGLIANI R GALIMBERTI A NICOLINI U
Citation
R. Cartolano et al., PRENATAL CONFIRMATION OF TRISOMY-12 MOSAICISM BY FETAL SKIN BIOPSY, Prenatal diagnosis, 13(11), 1993, pp. 1057-1059
Citations number
14
Categorie Soggetti
Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
13
Issue
11
Year of publication
1993
Pages
1057 - 1059
Database
ISI
SICI code
0197-3851(1993)13:11<1057:PCOTMB>2.0.ZU;2-M
Abstract
Trisomy 12 mosaicism diagnosed at 16 weeks' amniocentesis in a 42-year -old woman was not confirmed at 18 weeks' gestational age in amniotic fluid or fetal blood. Fetal skin biopsy performed at the same time did , however, allow the detection of trisomy 12 in 1 of 14 fibroblasts an alysed. Fetal skin biopsy can be included within the diagnostic proced ures to be performed when a level III mosaicism is found in the amniot ic fluid.