Coeliac plexus block (CPB) is one of the few neurolytic procedures tha
t is still considered very useful in managing chronic cancer pain. We
describe what we believe to be the fifth case in the literature of par
aplegia following coeliac plexus block with ethyl alcohol. Clinical an
d neurophysiological examination confirmed the hypothesis of an acute
myelopathy probably caused by ischemia due to involvement of Adamkievi
cz's artery. The seriousness of this neurological complication led us
to review the different pain-relieving strategies in pancreatic cancer
. Several medical and surgical procedures are available for advanced p
ancreatic cancer, yet none of them alone can be considered the therapy
of choice for all cases. Hence, only a multidisciplinary approach to
pancreatic cancer pain can help in making the most appropriate choice
for each patient.