Alzheimer's Disease (AD) is an age-related dementia that has received
increasing attention in recent years. The disease appears to be specif
ic for humans and, moreover, its causes are unknown. Studies of the di
sease are complicated by the fact that a reliable diagnosis depends on
post-mortem analysis of brain tissue, and useful animal or cell model
s are not yet available. This article discusses the possibility of usi
ng tau (a protein associated with the neurofibrillary tangles that are
an indicator of AD) as a tool for further pursuing the diagnosis and
treatment of the disease.