GENETIC-POLYMORPHISM OF THE SINGLE-LOCUS PROBES PL159-1 AND PL355-8

Citation
K. Pfaff et al., GENETIC-POLYMORPHISM OF THE SINGLE-LOCUS PROBES PL159-1 AND PL355-8, International journal of legal medicine, 106(3), 1993, pp. 163-167
Citations number
15
Categorie Soggetti
Pathology
ISSN journal
09379827
Volume
106
Issue
3
Year of publication
1993
Pages
163 - 167
Database
ISI
SICI code
0937-9827(1993)106:3<163:GOTSPP>2.0.ZU;2-I
Abstract
The genetic polymorphism of the single-locus probes pL159-1 (D18S17) a nd pL355-8 (D20S15) was investigated in 445 unrelated individuals usin g PstI as restriction enzyme. Fragment size calculations were obtained using the molecular weight size marker MW-SBH. The basic relationship between migration distance and molecular weight was transformed using an exponential function. Fragment size frequency data show 2 peaks fo r pL159-1 at 4.36kb (2.36%) and 4.67kb (6.29%) and one peak for pL355- 8 at 6.04 kb (5.73%). The rate of heterozygosity exceeded 70% for both probes.