T. Sandstrom et al., LIPOPOLYSACCHARIDE (LPS) INHALATION IN HEALTHY-SUBJECTS CAUSES BRONCHOALVEOLAR NEUTROPHILIA, LYMPHOCYTOSIS, AND FIBRONECTIN INCREASE, American journal of industrial medicine, 25(1), 1994, pp. 103-104
Eight healthy volunteers were exposed to purified lipopolysaccharide (
LPS) by controlled inhalation. Bronchoalveolar lavage (BAL) 3 hours af
ter exposure revealed a pronounced neutrophilia, increase in lymphocyt
es, fibronectin concentration, and decrease in alveolar macrophage pha
gocytosis, as compared to a reference BAL. (C) 1994 Wiley-Liss, Inc.