ON ENANTIOSELECTIVE DEPROTONATION - SYNTHESIS AND CRYSTAL-STRUCTURE OF A CHIRAL AMIDOLITHIUM TETRAHYDROFURAN COMPLEX

Authors
EDWARDS AJ HOCKEY S MAIR FS RAITHBY PR SNAITH R
Citation
Aj. Edwards et al., ON ENANTIOSELECTIVE DEPROTONATION - SYNTHESIS AND CRYSTAL-STRUCTURE OF A CHIRAL AMIDOLITHIUM TETRAHYDROFURAN COMPLEX, Journal of organic chemistry, 58(25), 1993, pp. 6942-6943
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
25
Year of publication
1993
Pages
6942 - 6943
Database
ISI
SICI code
0022-3263(1993)58:25<6942:OED-SA>2.0.ZU;2-L
Abstract
The enantioselective base (RR')-bis(1-phenylethyl)amidolithium (1) was crystallized from THF/hexane and characterized by X-ray crystallograp hy as a bis-THF-solvated cyclic dimer which adopts a conformation that maximizes methyllithium contacts, inconsistent with previous rational izations of its enantioselectivity in enolizations of cyclic ketones.