G. Larcos et al., THE SIGNIFICANCE OF ISOLATED GA-67 UPTAKE IN THE HILAR LYMPH-NODES OFAN UNTREATED LYMPHOMA PATIENT, Clinical nuclear medicine, 18(12), 1993, pp. 1039-1041
A 69-year-old woman presented with non-Hodgkin's lymphoma of the right
illoinguinal region in whom bilateral uptake of Ga-67 in hilar lymph
nodes was noted on thoracic SPECT. There were no Ga-67 abnormalities e
lsewhere within the thorax, and a chest CT scan was also normal. The p
atient received radiotherapy to the inguinal region and remained in cl
inical remission for 28 months following treatment. She subsequently r
elapsed at a number of peripheral lymph node sites, but not in the che
st. The authors postulate that isolated hilar uptake of Ga-67 SPECT ma
y not be clinically significant in some untreated patients with lympho
ma. This scintigraphic finding should be interpreted cautiously, parti
cularly when other chest imaging studies remain negative.