A. Put et al., CLINICAL EFFICACY OF ESSENTIAL PHOSPHOLIPIDS IN PATIENTS CHRONICALLY EXPOSED TO ORGANIC-SOLVENTS, Journal of international medical research, 21(4), 1993, pp. 185-191
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy","Medicine, Research & Experimental
A total of 45 workers, who had been chronically exposed to a potential
ly hepatotoxic xylene - toluene - benzene mixture in the atmosphere, w
ere treated for 3 months with 'essential' phospholipids. Routine bioch
emical tests and radioisotope investigations to assess liver damage we
re carried out both at baseline and after treatment. The liver:spleen
index was increased in 71% of subjects and the mean isotope transit ti
me in the liver was reduced in 90% of the patients after treatment. Th
e biochemical parameters remained within the normal range throughout t
he treatment period. The results suggest that 'essential' phospholipid
s may be of value in the treatment of liver damage that has arisen as
a result of chronic exposure to organic solvents.