SYSTEMIC LUPUS-ERYTHEMATOSUS IN A RHESUS MACAQUE

Authors
ANDERSON ST KLEIN EC
Citation
St. Anderson et Ec. Klein, SYSTEMIC LUPUS-ERYTHEMATOSUS IN A RHESUS MACAQUE, Arthritis and rheumatism, 36(12), 1993, pp. 1739-1742
Citations number
16
Categorie Soggetti
Rheumatology
Journal title
Arthritis and rheumatism → ACNP
ISSN journal
00043591
Volume
36
Issue
12
Year of publication
1993
Pages
1739 - 1742
Database
ISI
SICI code
0004-3591(1993)36:12<1739:SLIARM>2.0.ZU;2-E
Abstract
We describe the clinical course and histopathologic findings in a rhes us macaque (Macaca mulatta) which developed a systemic inflammatory di sorder resembling systemic lupus erythematosus (SLE). The manifestatio ns of the SLE included antinuclear antibody, hemolytic anemia, membran oproliferative glomerulonephritis, and arthritis. To our knowledge, sp ontaneously occurring SLE has not previously been described in nonhuma n primates.