ANTIDIARRHEAL ACTIVITY OF THE METHANOLIC FRACTION OF THE EXTRACT OF UNRIPE FRUITS OF PSIDIUM-GUAJAVA LINN

Authors
GHOSH TK SEN T DAS A DUTTA AS CHAUDHURI AKN
Citation
Tk. Ghosh et al., ANTIDIARRHEAL ACTIVITY OF THE METHANOLIC FRACTION OF THE EXTRACT OF UNRIPE FRUITS OF PSIDIUM-GUAJAVA LINN, PTR. Phytotherapy research, 7(6), 1993, pp. 431-433
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
7
Issue
6
Year of publication
1993
Pages
431 - 433
Database
ISI
SICI code
0951-418X(1993)7:6<431:AAOTMF>2.0.ZU;2-B
Abstract
The methanolic fraction of the extract of unripe fruits of Psidium gua java was found to possess significant antidiarrhoeal activity. The fra ction decreased gastric motility in an experimental animal model and i nhibited acetylcholine release from isolated guinea-pig ileum. On micr obial screening the fraction was found to inhibit significantly the gr owth of different strains of Shigella spp. and Vibrio cholerae.