HEPATOCELLULAR-CARCINOMA - IDENTIFYING AND SCREENING POPULATIONS AT INCREASED RISK

Hepatocellular carcinoma appears to be associated with hepatitis B and C infections and is common in patients with cirrhosis caused by chron ic viral hepatitis. Screening for hepatocellular carcinoma can lead to early detection and surgical intervention, resulting in improved surv ival rates. Patients with cirrhosis or unexplained elevation of alpha- fetoprotein levels should be examined every 3 to 6 months. Patients wi th chronic viral hepatitis but no underlying liver disease and normal levels of alpha fetoprotein may be examined yearly. Seronegative conta cts of hepatitis B virus carriers should be immunized.