Among the various therapies for chronic bronchitis none is more import
ant, both for relieving symptoms and for preserving pulmonary function
, than cessation of cigarette smoking. Unfortunately, even when patien
ts are motivated and programs are aggressive, results are unspectacula
r. Chronic bronchitis often responds favorably to bronchodilating agen
ts. For initial therapy, ipratropium bromide (Atrovent) is the agent o
f choice because of its efficacy and safety. The role of anti-inflamma
tory drugs is not yet clear, although inhaled steroids are beneficial
in some patients. Most patients improve with smoking cessation and/or
judicious pharmacologic intervention.