Mj. Silver et al., REDUCTION OF BLOOD-LOSS FROM DIAGNOSTIC SAMPLING IN CRITICALLY ILL PATIENTS USING A BLOOD-CONSERVING ARTERIAL LINE SYSTEM, Chest, 104(6), 1993, pp. 1711-1715
Study objective: To demonstrate the utility of a new blood-conserving
arterial line system in reducing blood loss associated with blood draw
ing in the critical care setting. Design: Prospective, randomized, cro
ssover comparison between two arterial line systems. Setting: Medical
intensive care unit (ICU); tertiary care teaching institution. Patient
s: Thirty-one patients who required invasive arterial blood pressure m
onitoring throughout their ICU course. Interventions: For ICU days 1 t
o 2, patients were randomized to receive either a conventional arteria
l line system or a new blood-conserving arterial line system. On ICU d
ays 3 to 7, patients with a conventional arterial line were crossed ov
er to the blood-conserving arterial line, and vice versa. Laboratory b
lood volumes, mixed discard volumes, and blood discard volumes were th
en recorded to document how much blood loss is associated with each as
pect of the blood sampling process. Results: The mean total volume of
blood sent to the laboratory for testing was 257.4 ml. As a result of
''clearing the line'' over the 7-day period, patients with the convent
ional arterial line system lost a mean volume of 340.2 ml of blood mix
ed with heparinized saline solution more than patients with the blood-
conserving arterial line. In terms of the blood component of the blood
-heparinized saline solution mixture, use of the conventional arterial
line was associated with an average of 156.8 ml more blood discarded
than with the blood-conserving arterial line. Conclusion: The new bloo
d-conserving arterial line system provides a simple and effective meth
od for reducing blood loss related to diagnostic sampling in the criti
cal care setting.