RADIOLOGIC ABNORMALITIES OF THE STERNUM IN TURNERS-SYNDROME

Citation
Av. Mehta et al., RADIOLOGIC ABNORMALITIES OF THE STERNUM IN TURNERS-SYNDROME, Chest, 104(6), 1993, pp. 1795-1799
Citations number
10
Categorie Soggetti
Respiratory System
Journal title
ChestACNP
ISSN journal
00123692
Volume
104
Issue
6
Year of publication
1993
Pages
1795 - 1799
Database
ISI
SICI code
0012-3692(1993)104:6<1795:RAOTSI>2.0.ZU;2-9
Abstract
Various skeletal abnormalities, including chest deformity, have been r eported with Turner's syndrome. We report radiologic findings of the s ternum on lateral chest roentgenograms in 15 children and adolescents with Turner's syndrome, whose ages ranged between 2 weeks and 20 years . Eight had associated congenital heart disease (CHD). Twelve patients (80 percent) had various sternal abnormalities; 5 had short sternum, 3 had premature fusion of the manubrio-sternal junction, and 4 had pre mature fusion of the mesosternum. Five had decreased ratio of sternal body to manubrium. Three patients had two ossification centers of the manubrium. Four patients had bowing of the mesosternum; three of these had mild pectus excavatum also. In this series, children with and wit hout CHD had similar sternal abnormalities. Although not pathognomonic , sternal abnormalities on a lateral chest roentgenogram are common sk eletal abnormalities associated with Turner's syndrome and are indepen dent of associated CHD. In our series of 15 patients, 10 had monosomy (45,X) on blood karyotype; 7 of them had associated CHD. This is the f irst systematic analysis of radiologic abnormalities of the sternum in Turner's syndrome and includes findings not previously reported.