Ml. Brigden et al., EVALUATION OF THE SYSMEX NE-8000 - AUTOMATED HEMATOLOGY ANALYZER IN AHIGH-VOLUME OUTPATIENT LABORATORY, American journal of clinical pathology, 100(6), 1993, pp. 618-625
An evaluation of SYSMEX NE-8000 (Toa Medical Electronics Co., Ltd., Ko
be, Japan) hematology analyzer, including its automated five-part whit
e blood cell (WBC) differential count, was performed in a high-volume
outpatient laboratory. Precision, mixing studies, stability, carry-ove
r, and linearity were all within the limits stated by the manufacturer
. Evaluation of the five-part WBC differential revealed excellent corr
elation with manual differential neutrophil and lymphocyte counts. Mon
ocyte, eosinophil, and basophil data were acceptable given the known p
oor precision of 200 cell manual WBC differential counts when low perc
entages of individual cell types are present. Overall, flagging for mo
rphologic abnormalities displayed a sensitivity of 87% and a specifici
ty of 97%. The combination of the flagging system with the visual reco
rd provided by the NE-8000 WBC histogram represents an effective tool
for separating normal from abnormal specimens, and allows considerable
selectivity in the performance of follow-up manual WBC differential c
ounts.