LONG-TERM RESULTS OF DANISH-PROSTATIC-CANCER-GROUP TRIAL-86

In a multicenter trial conducted by the Danish Prostatic Cancer Group, 264 patients with advanced prostate cancer were randomized either to undergo bilateral orchiectomy or to receive combination treatment with goserelin acetate and flutamide. This report is an update of that stu dy, covering a median follow-up for survival of 57 months. Of 262 pati ents who were evaluated, 208 have died. As noted in earlier analyses o f this study, no differences in time to progression and cause-specific and overall survival could be identified between the two treatment gr oups. In conclusion, the combination of goserelin and flutamide was no t clinically superior to bilateral orchiectomy in the treatment of adv anced prostate cancer.