Bj. Wiatrak et al., RADIATION-THERAPY AS AN ALTERNATIVE TO SURGERY IN THE MANAGEMENT OF INTRACRANIAL JUVENILE NASOPHARYNGEAL ANGIOFIBROMA, International journal of pediatric otorhinolaryngology, 28(1), 1993, pp. 51-61
Juvenile nasopharyngeal angiofibroma is a benign, vascular tumor which
typically presents in adolescent males. Although surgical resection i
s usually recommended for the management of this tumor, external beam
radiation therapy has also been advocated in the literature. We report
three cases of large juvenile nasopharyngeal angiofibromas with exten
sive intracranial extension primarily managed with external beam radia
tion therapy. Although there was not complete resolution of the tumors
, there was significant alleviation of symptomatology with no serious
side effects from the radiation therapy. Based on these cases, we feel
that external beam radiation therapy in the management of extensive j
uvenile nasopharyngeal angiogibromas with intracranial extension is wa
rranted in certain select cases.