A NOVEL ADHESION PROTEIN EXPRESSED BY CILIATED EPITHELIUM, HEMOCYTES,AND LEUKEMIA-CELLS IN SOFT-SHELL CLAMS

Authors
SMOLOWITZ RM REINISCH CL
Citation
Rm. Smolowitz et Cl. Reinisch, A NOVEL ADHESION PROTEIN EXPRESSED BY CILIATED EPITHELIUM, HEMOCYTES,AND LEUKEMIA-CELLS IN SOFT-SHELL CLAMS, Developmental and comparative immunology, 17(6), 1993, pp. 475-481
Citations number
17
Categorie Soggetti
Immunology
Journal title
Developmental and comparative immunology → ACNP
ISSN journal
0145305X
Volume
17
Issue
6
Year of publication
1993
Pages
475 - 481
Database
ISI
SICI code
0145-305X(1993)17:6<475:ANAPEB>2.0.ZU;2-G
Abstract
The ontogeny of circulating hemocytes and tumor cells in mollusks has been approached using monoclonal antibodies to normal cells. A monoclo nal antibody, previously shown to identify an adhesion related protein (p130), has been used to define the reactivity of cells in tissues fr om normal soft-shell clams (Mya arenaria) and soft-shell clams with le ukemia. Using immunoperoxidase technology, we have determined that hem ocytes, connective tissue cells, and a subset of leukemia cells that a re adherent share a cross-reactive epitope with cilia.