Study Objective: To evaluate the ability of arterial waveform contour
analysis to measure cardiac output (CO) continuously in postoperative
critically ill patients. Design: Thermodilution CO (TDCO) measurements
were compared with simultaneous pulse contour CO (PCCO) measurements.
Setting: University hospital surgical intensive care unit. Patients:
29 critically ill surgical patients with indwelling systemic arterial
and pulmonary artery catheters. Measurements and Main Results: TDCO me
asurements were compared with PCCO at 1- to and-hour intervals. Mean T
DCO was 5.75 +/- 1.79 L/min, and mean PCCO was 5.76 +/- 1.83 Limin. An
alysis of the difference between TDCO and PCCO showed a bias of 0.01 /- 0.5 L/min. Comparison of the difference between pairs of sequential
TDCO measurements and the initial TDCO and subsequent PCCO measuremen
ts resulted in a correlation coefficient of 0.64. Conclusions: The PCC
O method appears to be able to estimate changes in CO under the condit
ions tested, in which PCCO was recalibrated after each TDCO measuremen
t. However, limitations of this method in the immediate postoperative
period following aortic aneurysm surgery were identified.