A NEO-DARWINIAN ALGORITHM - ASYMMETRICAL MUTATIONS DUE TO SEMICONSERVATIVE DNA-TYPE REPLICATION PROMOTE EVOLUTION

Citation
K. Wada et al., A NEO-DARWINIAN ALGORITHM - ASYMMETRICAL MUTATIONS DUE TO SEMICONSERVATIVE DNA-TYPE REPLICATION PROMOTE EVOLUTION, Proceedings of the National Academy of Sciences of the United Statesof America, 90(24), 1993, pp. 11934-11938
Citations number
14
Categorie Soggetti
Multidisciplinary Sciences
ISSN journal
00278424
Volume
90
Issue
24
Year of publication
1993
Pages
11934 - 11938
Database
ISI
SICI code
0027-8424(1993)90:24<11934:ANA-AM>2.0.ZU;2-S
Abstract
Evolution is, in a sense, to resolve optimization problems. Our neo-Da rwinian algorithm based on the mechanics of inheritance and natural se lection uses double-stranded DNA-type genetic information to resolve t he ''knapsack problem.'' The algorithm with asymmetrical mutations due to semiconservative DNA-type replication most effectively resolved th e problem. Our results strongly suggest that disparity in mutations ca used by the asymmetric machinery of DNA replication promotes evolution , in particular of diploid organisms with a high mutation rate, in a s mall population, and under strong selection pressure.