CHOLESTENO INDOLES .1. PREPARATION OF 1'H -5-ALPHA-CHOLEST-2-ENO[3,2-B]INDOLES

Citation
J. Samu et al., CHOLESTENO INDOLES .1. PREPARATION OF 1'H -5-ALPHA-CHOLEST-2-ENO[3,2-B]INDOLES, Liebigs Annalen der Chemie, (11), 1993, pp. 1225-1227
Citations number
13
Categorie Soggetti
Chemistry
Journal title
ISSN journal
01702041
Issue
11
Year of publication
1993
Pages
1225 - 1227
Database
ISI
SICI code
0170-2041(1993):11<1225:CI.PO1>2.0.ZU;2-N
Abstract
1'H-5alpha-Cholest-2-eno[3,2-b]indole (1a), the corresponding N-methyl , N-acetyl, and N-formyl compounds 1b-d, as well as the respective met hoxy derivatives 2b-5d have been synthesized as model compounds for in tended CD investigations. Application of the Fischer indole synthesis afforded the compounds 1a-5a which were N-methylated to 1b-5b, N-acety lated to 1c-5c, and N-formylated to 1d-5d.