INTRACYTOPLASMIC INCLUSION-BODIES OF ERYTHROCYTE ORIGIN WITHIN HEPATOCYTES IN A HEPATIC ALLOGRAFT

Authors
KHETTRY U FEDERMAN M OHARA CJ LANDIS WJ
Citation
U. Khettry et al., INTRACYTOPLASMIC INCLUSION-BODIES OF ERYTHROCYTE ORIGIN WITHIN HEPATOCYTES IN A HEPATIC ALLOGRAFT, Ultrastructural pathology, 17(6), 1993, pp. 593-598
Citations number
19
Categorie Soggetti
Microscopy,Pathology
Journal title
Ultrastructural pathology → ACNP
ISSN journal
01913123
Volume
17
Issue
6
Year of publication
1993
Pages
593 - 598
Database
ISI
SICI code
0191-3123(1993)17:6<593:IIOEOW>2.0.ZU;2-9
Abstract
Intracytoplasmic inclusion bodies with an unusual immunohistochemical profile, histologically similar to alpha1 antitrypsin globules and meg amitochondria, were seen within hepatocytes in a liver allograft biops y. Electron microscopy revealed that these structures were erythrocyte s in various stages of degradation. Their appearance following an epis ode of Pneumocystis carinii pneumonia suggests a possible relationship between bouts of hypoxia and erythrocyte entry into hepatocytes.