MACROPHAGE ELIMINATION INCREASES BACTERIAL TRANSLOCATION AND GUT-ORIGIN SEPTICEMIA BUT ATTENUATES SYMPTOMS AND MORTALITY-RATE IN A MODEL OFSYSTEMIC INFLAMMATION

Authors
NIEUWENHUIJZEN GAP HASKEL Y LU Q BERG RD VANROOIJEN N GORIS RJA DEITCH EA
Citation
Gap. Nieuwenhuijzen et al., MACROPHAGE ELIMINATION INCREASES BACTERIAL TRANSLOCATION AND GUT-ORIGIN SEPTICEMIA BUT ATTENUATES SYMPTOMS AND MORTALITY-RATE IN A MODEL OFSYSTEMIC INFLAMMATION, Annals of surgery, 218(6), 1993, pp. 791-799
Citations number
28
Categorie Soggetti
Surgery
Journal title
Annals of surgery → ACNP
ISSN journal
00034932
Volume
218
Issue
6
Year of publication
1993
Pages
791 - 799
Database
ISI
SICI code
0003-4932(1993)218:6<791:MEIBTA>2.0.ZU;2-D
Abstract
The central question tested in this study was whether dichloromethylen e-diphosphonate (CL(2)MDP) liposome-mediated elimination of hepatic an d splenic macrophages would influence zymosan-induced bacterial transl ocation and the zymosan-induced generalized inflammatory response.