ACQUIRED CYSTIC-DISEASE AND RENAL ADENOCARCINOMA FOLLOWING RENAL-TRANSPLANTATION

Acquired renal cystic disease has been associated with the development of renal cell carcinoma in patients on chronic dialysis. The disease has been documented to regress in the native kidney after successful r enal transplantation. We report 4 cases of renal cell carcinoma occurr ing in the native kidney 3 to 8 years after successful renal transplan tation. Of these patients 3 also had acquired cystic disease of the na tive kidney. These 3 cases suggest that the malignant potential associ ated with acquired renal cystic disease may not be reduced significant ly by renal transplantation and that periodic imaging of the native ki dney is advisable after transplantation, particularly when the disease is present before transplantation.