Since 1985 several European Institutes of Forensic Medicine have coope
rated in a multicenter study providing a constant monitoring of HIV-1
prevalence among drug-related deaths. From 1985 to 1991 the HIV status
of 5372 drug-related fatalities (4328 males, 1044 females) has been t
ested. A total of 764 (14%) drug deaths were HIV-positive (13% of the
males, 21% of the females). In contrast to the steadily increasing num
ber of drug-related fatalities the HIV-1 prevalence is decreasing, esp
ecially in the German cities. Regional differences are obvious. The de
velopment of the HIV prevalence of drug deaths is comparable with that
of the still living intravenous drug addicts.