In an interdisciplinary study, 53 cases of drug-related death were inv
estigated. Forty per cent of these cases exhibited acute or chronic he
patitis; foreign body granulomas were detected in 30%. By CT-scan of t
he left lung, small abscesses and pneumonic focuses could be localized
. The spectrum of bacterial strains isolated from lung tissue did not
differ significantly from that of a control group. Severe alterations
of the testes, i.e. reduction of spermatogenesis, was present in a con
siderable number of cases. The high rate of myocarditis diagnosed (18%
) supports the idea that besides acute intoxication, drug-related deat
h is due to multifactorial origin.