Background The pathogenesis of cervical artery dissection remains unkn
own. Infection-mediated damage of the arterial wall may be one contrib
uting mechanism. We present three male patients with respiratory infec
tion prior to cervical artery dissection. Case Descriptions Case 1: Du
ring an upper respiratory tract infection, a 49-year-old patient devel
oped bilateral carotid and vertebral artery dissection with complete v
essel restitution. Case 2: Within 3 years, a 40-year-old patient exper
ienced two episodes of bilateral internal carotid artery dissection, b
oth preceded by febrile upper respiratory tract infection. Case 3: A 5
2-year-old patient developed right-sided and, 2 years later, left-side
d internal carotid artery dissection, each following upper respiratory
tract infection. Conclusions Infection may be a trigger factor in the
pathogenesis of cervical artery dissection.