A systematic methodology is presented for the optimal design of stable
systems. The methodology is based upon the formulation of a parametri
c problem that bounds the optimal stable solution to which it converge
s within a number of iterations. The approach can be applied to the op
timal design of total process flowsheets, as well as to the optimal sy
nthesis of reactor networks where it can simultaneously address optimi
zation and stability issues in superstructures comprised by large numb
ers of interconnected reactors which process complex reaction schemes.