THROMBOSIS-INDUCING ACTIVITY - A FACTOR WHICH APPEARS IN PLASMA OF PATIENTS WITH ALLERGIC-ASTHMA DURING ATTACK

Thrombosis-inducing activity (TIA) is a factor which was recently iden tified in plasma from patients with advanced lung cancer and acute res piratory tract infection. In the present study, TIA was measured durin g periods of attack and nonattack in patients with the allergic and no nallergic type of asthma and pulmonary emphysema with an asthmatic com ponent. In the allergic type of asthma, the attack was accompanied by the appearance of TIA, but when the attack ended it disappeared from p lasma. In the nonallergic type of asthma and emphysema with an asthmat ic component, TLA remained negative even during the attack. These obse rvations indicate that TIA has some correlations with allergic asthma.