A CASE OF SYSTEMIC-SCLEROSIS WITH ANTICENTROMERE, ANTITOPOISOMERASE-I, AND ANTI-U1RNP ANTIBODIES

Authors
SATO S IHN H SOMA Y SHIMOZUMA M SHISHIBA T TAKEHARA K
Citation
S. Sato et al., A CASE OF SYSTEMIC-SCLEROSIS WITH ANTICENTROMERE, ANTITOPOISOMERASE-I, AND ANTI-U1RNP ANTIBODIES, Journal of rheumatology, 20(11), 1993, pp. 1961-1963
Citations number
15
Categorie Soggetti
Rheumatology
Journal title
Journal of rheumatology → ACNP
ISSN journal
0315162X
Volume
20
Issue
11
Year of publication
1993
Pages
1961 - 1963
Database
ISI
SICI code
0315-162X(1993)20:11<1961:ACOSWA>2.0.ZU;2-K
Abstract
We describe a case of systemic sclerosis (SSc) positive for 3 autoanti bodies; anticentromere antibody, antitopoisomerase I antibody, and ant i-U1RNP antibody. It is known that coexistence of 2 of these 3 antibod ies is rare and the coexistence of these 3 antibodies in serum from a patient with SSc has not been reported. In addition, we examined our s tock serum samples from 236 cases with SSc or related disorders for th e presence of specific antinuclear antibodies and were unable to find a serum sample containing all 3 antibodies.