The nonvolatile fraction of the dichloromethane extract of ginger rhiz
omes exhibited a strong antioxidative activity using linoleic acid as
the substrate in ethanol-phosphate buffer solution. The fraction was p
urified by chromatographic techniques to provide five gingerol related
compounds and eight diarylheptanoids. Among them, 12 compounds exhibi
ted higher activity than alpha-tocopherol. The activity was probably d
ependent upon side chain structures and substitution patterns on the b
enzene ring.