IFOSFAMIDE-INDUCED RENAL TUBULAR DEFECT

Authors
VALDIVIESO MJT PEREZ JL MELERO C VIVANCO JL MULEY R VARA J
Citation
Mjt. Valdivieso et al., IFOSFAMIDE-INDUCED RENAL TUBULAR DEFECT, Medical and pediatric oncology, 22(2), 1994, pp. 144-146
Citations number
23
Categorie Soggetti
Oncology,Pediatrics
Journal title
Medical and pediatric oncology → ACNP
ISSN journal
00981532
Volume
22
Issue
2
Year of publication
1994
Pages
144 - 146
Database
ISI
SICI code
0098-1532(1994)22:2<144:IRTD>2.0.ZU;2-T
Abstract
We describe 2 cases of proximal tubular defects induced by the adminis tration of ifosfamide at a dosage of 6 g/m2/course over 2 days in chil dren with a diagnosis of malignant mesenchymal tumors. This adverse ef fect could be minimized dividing dosage of the drug. However at presen t it is not clear if divided doses are completely safe. (C) 1994 Wiley -Liss, Inc.