A NEW METHOD FOR THE PREPARATION OF TETRAZOLES FROM NITRILES USING TRIMETHYLSILYLAZIDE TRIMETHYLALUMINUM/

Authors
HUFF BE STASZAK MA
Citation
Be. Huff et Ma. Staszak, A NEW METHOD FOR THE PREPARATION OF TETRAZOLES FROM NITRILES USING TRIMETHYLSILYLAZIDE TRIMETHYLALUMINUM/, Tetrahedron letters, 34(50), 1993, pp. 8011-8014
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
50
Year of publication
1993
Pages
8011 - 8014
Database
ISI
SICI code
0040-4039(1993)34:50<8011:ANMFTP>2.0.ZU;2-K
Abstract
Tetrazoles are prepared in good yields from alkyl and aryl nitriles by treatment with equimolar trimethylaluminum and trimethylsilylazide. Y ields, substrate compatibility, and reaction temperature are comparabl e with the use of other metal azides such as Al(N-3)(3) and n.Bu(3)SnN (3). The reactions are run in toluene or with added THF at 80 degrees C.