CONVENIENT SYNTHESIS OF N-METHYL-3-(2-ETHENYLPHENYL)-1(2H)ISOQUINOLONES, KEY MODELS FOR THE ELABORATION OF THE BENZO[C]PHENANTHRIDINONE ANDPHENANTHRIDINE SKELETONS
A. Couture et al., CONVENIENT SYNTHESIS OF N-METHYL-3-(2-ETHENYLPHENYL)-1(2H)ISOQUINOLONES, KEY MODELS FOR THE ELABORATION OF THE BENZO[C]PHENANTHRIDINONE ANDPHENANTHRIDINE SKELETONS, Tetrahedron letters, 34(50), 1993, pp. 8097-8100
A variety of N-methyl-3-(2-ethenylphenyl)-1(2H)-isoquinolones 1a-e hav
e been prepared by base-induced intramolecular cyclization of N-(2-eth
enylbenzoyl)-N,2-dimethylbenzamide derivatives 2a-e. The concomitant f
ormation of the fused dihydro benzo[c]phenanthridinones 7a-e was also
observed during this process.