DIRECTED ASYMMETRIC REDUCTION OF A CARBONYL GROUP VIA A NEW HOMOCHIRAL BORONATE ESTER

Authors
MEARS RJ WHITING A
Citation
Rj. Mears et A. Whiting, DIRECTED ASYMMETRIC REDUCTION OF A CARBONYL GROUP VIA A NEW HOMOCHIRAL BORONATE ESTER, Tetrahedron letters, 34(50), 1993, pp. 8155-8156
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
50
Year of publication
1993
Pages
8155 - 8156
Database
ISI
SICI code
0040-4039(1993)34:50<8155:DAROAC>2.0.ZU;2-S
Abstract
Homochiral beta-boronate carbonyl derivative 4 directs the asymmetric reduction of the ketone moiety, providing 89 % enantiomeric excess of the (S)-diol 6, using borane-tetrahydrofuran as the reducing agent.