FAMILIAL SYNDACTYLY TYPE-III - REPORT OF A LARGE PEDIGREE

We present a pedigree containing 14 cases of familial syndactyly of th e ring and little finger (Type III syndactyly). Three of these were tr eated surgically in this unit, and a fourth had previously been treate d elsewhere by the senior author of this paper. Analysis of the pedigr ee confirms the autosomal dominant nature of the genetic defect, while clinical study reveals variable phenotypical expression. This is one of the largest pedigrees yet reported for this variety of syndactyly.