Wsj. Uijttewaal et al., LATERAL MIGRATION OF BLOOD-CELLS AND MICROSPHERES IN 2-DIMENSIONAL POISEUILLE FLOW - A LASER-DOPPLER STUDY, Journal of biomechanics, 27(1), 1994, pp. 35-42
The inertia-induced lateral migration of rigid microspheres, platelets
and erythrocytes is studied experimentally. The concentration and vel
ocity profiles of the particles have been determined with a laser-Dopp
ler anemometer designed for high resolution measurements. Data are com
pared with empirical and analytical models on inertia-induced lateral
migration of rigid spheres. Experiments done in rectangular flow chann
els of high aspect ratio reveal that at a sufficiently high particle R
eynolds number, platelets exhibit tubular pinch effects comparable wit
h those of rigid polystyrene microspheres. Erythrocytes also exhibit i
nertia-induced lateral migration at high particle Reynolds number and
low medium viscosity. At a higher medium viscosity, erythrocytes show
deformation-induced lateral migration towards the center of the flow c
hannel.