LATERAL MIGRATION OF BLOOD-CELLS AND MICROSPHERES IN 2-DIMENSIONAL POISEUILLE FLOW - A LASER-DOPPLER STUDY

Citation
Wsj. Uijttewaal et al., LATERAL MIGRATION OF BLOOD-CELLS AND MICROSPHERES IN 2-DIMENSIONAL POISEUILLE FLOW - A LASER-DOPPLER STUDY, Journal of biomechanics, 27(1), 1994, pp. 35-42
Citations number
19
Categorie Soggetti
Engineering, Biomedical",Biophysics
Journal title
ISSN journal
00219290
Volume
27
Issue
1
Year of publication
1994
Pages
35 - 42
Database
ISI
SICI code
0021-9290(1994)27:1<35:LMOBAM>2.0.ZU;2-P
Abstract
The inertia-induced lateral migration of rigid microspheres, platelets and erythrocytes is studied experimentally. The concentration and vel ocity profiles of the particles have been determined with a laser-Dopp ler anemometer designed for high resolution measurements. Data are com pared with empirical and analytical models on inertia-induced lateral migration of rigid spheres. Experiments done in rectangular flow chann els of high aspect ratio reveal that at a sufficiently high particle R eynolds number, platelets exhibit tubular pinch effects comparable wit h those of rigid polystyrene microspheres. Erythrocytes also exhibit i nertia-induced lateral migration at high particle Reynolds number and low medium viscosity. At a higher medium viscosity, erythrocytes show deformation-induced lateral migration towards the center of the flow c hannel.