MODIFICATION OF THE DRUGS MUTAGENICITY BY THEIR IMMOBILIZATION - THE EFFECT OF ANALGIN IMMOBILIZED IN STARCH IN MICE

Authors
MIKHEEV VS TOGO EF POLKINA SI
Citation
Vs. Mikheev et al., MODIFICATION OF THE DRUGS MUTAGENICITY BY THEIR IMMOBILIZATION - THE EFFECT OF ANALGIN IMMOBILIZED IN STARCH IN MICE, Genetika, 29(11), 1993, pp. 1933-1935
Citations number
4
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
29
Issue
11
Year of publication
1993
Pages
1933 - 1935
Database
ISI
SICI code
0016-6758(1993)29:11<1933:MOTDMB>2.0.ZU;2-N
Abstract
The mutagenic effect of analgin was studied in germ and somatic cells of male mice Mus musculus, It was found that injection of analgin (20 and 40 mg per mouse) significantly increased the frequency of sperm he ad anomalies and chromosome aberrations in bone marrow cells. Immobili zation of analgin in starch led to, decrease in the drug immobilizatio n.