PATHOGENETIC FEATURES OF ARTERIAL-HYPERTE NSION IN PATIENTS OF YOUNG AGE (DATA OF ACUTE PERORAL SALT LOADS)

Acute peroral salt loads were carried out in 73 persons (age: 15-30 ye ars). Results indicate the leading role of genetic influences in chang es of the main parameters of the water-salt homeostasis in formation o f the pathological background of hypertensive disease, especially at t he first stages of the disease or in increased risk, i. e. in subjects with normal AP and heredity risk for hypertensive disease and in thos e with borderline arterial hypertension, show an unstable regulation o f the water-salt homeostasis with tendencies to sodium retention or it s increased excretion. At the late stages advancing retention of sodiu m is dominatin.