A clinico-morphological study was made of processes in the gastro-duod
enal mucosa during treatment of duodenal ulcer by de-nol. Results indi
cate that the dyspeptic and pain syndrome disappeared after de-nol tre
atment within 4-7 days in 78.3 % of patients, the ulcer scarred in the
course of 21.4 days. Advantages of de-nol treatment are shown electro
n-microscopically, by studying biopsy specimens of the mucosa before a
nd after treatment.