M. Sturdikova et al., REGULATION OF BIOSYNTHESIS OF 1-ACETYL-BETA-CARBOLINE IN STREPTOMYCES-KASUGAENSIS, Biotechnology letters, 15(12), 1993, pp. 1237-1242
Biosynthesis of 1-acetyl-beta-carboline, an enzyme inhibitor, in S. ka
sugaensis SK-619 was regulated by quality of the carbon source and by
addition of organic acids into medium. Variation in phosphate concentr
ation also affected production of this carboline.