KINETIC RESOLUTION OF OXIRANES BY USE OF CHIRAL LEWIS-ACID CATALYSTS

Authors
BRUNNER M MUSSMANN L VOGT D
Citation
M. Brunner et al., KINETIC RESOLUTION OF OXIRANES BY USE OF CHIRAL LEWIS-ACID CATALYSTS, Synlett, (12), 1993, pp. 893-894
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
12
Year of publication
1993
Pages
893 - 894
Database
ISI
SICI code
0936-5214(1993):12<893:KROOBU>2.0.ZU;2-4
Abstract
The kinetic resolution of oxiranes by use of chiral Lewis acid catalys ts is described. Improved stereoselectivities are observed in the nucl eophilic ring opening of oxiranes with secondary amines. For the first time the enantioselective insertion of CO2 into the oxirane ring form ing enantiomerically enriched 1,3-dioxolanones was achieved applying c hirally modified Zr- and Ti-complexes.