A SIMPLE ENANTIOSELECTIVE SYNTHESIS OF (-)-S-CAMPHONANIC AND (-R-CAMPHONANIC ACIDS())

Authors
ABAD A AGULLO C ARNO M CUNAT AC ZARAGOZA RJ
Citation
A. Abad et al., A SIMPLE ENANTIOSELECTIVE SYNTHESIS OF (-)-S-CAMPHONANIC AND (-R-CAMPHONANIC ACIDS()), Synlett, (12), 1993, pp. 895-896
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
12
Year of publication
1993
Pages
895 - 896
Database
ISI
SICI code
0936-5214(1993):12<895:ASESO(>2.0.ZU;2-D
Abstract
A four step enantioselective synthesis of 1S- and IR-1,2,2-trimethylcy clopentanecarboxylic acids [(S)- and (R)-camphonanic acid, (-)-1 and ( +)-1 respectively] has been achieved from beta-cyclogeraniol, using a Katsuki-Sharpless asymmetric epoxidation and a pinacollic rearrangemen t as key synthetic steps.