ALPHA-VINYL BETA-LACTAMS - CONVENIENT ELABORATION OF THE THIENAMYCIN SIDE-CHAIN

Citation
Ak. Bose et al., ALPHA-VINYL BETA-LACTAMS - CONVENIENT ELABORATION OF THE THIENAMYCIN SIDE-CHAIN, Synlett, (12), 1993, pp. 897-899
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
09365214
Issue
12
Year of publication
1993
Pages
897 - 899
Database
ISI
SICI code
0936-5214(1993):12<897:AB-CEO>2.0.ZU;2-N
Abstract
Beta-lactams with the thienamycin side chain were synthesized from alp ha-vinyl beta-lactams via oxymercuration-demercuation reaction as well as through their epoxidation, regioselective epoxide ring cleavage an d radical-induced debromination. The stereochemistry of these beta-lac tams was established by physico-chemical methods.