INVERSION OF CIS-SUBSTITUTED ALPHA-CYCLOPROPYL ACYL ANION - STEREOSELECTIVE ENTRY TO THE SYNTHESIS OF A POTENT METABOTROPIC GLUTAMATE AGONIST, (2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE (L-CCG-I), AND ITS 3'-SUBSTITUTED ANALOGS

Authors
SHIMAMOTO K OHFUNE Y
Citation
K. Shimamoto et Y. Ohfune, INVERSION OF CIS-SUBSTITUTED ALPHA-CYCLOPROPYL ACYL ANION - STEREOSELECTIVE ENTRY TO THE SYNTHESIS OF A POTENT METABOTROPIC GLUTAMATE AGONIST, (2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE (L-CCG-I), AND ITS 3'-SUBSTITUTED ANALOGS, Synlett, (12), 1993, pp. 919-920
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
12
Year of publication
1993
Pages
919 - 920
Database
ISI
SICI code
0936-5214(1993):12<919:IOCAAA>2.0.ZU;2-#
Abstract
Stereoselective method for the synthesis of L-CCG-I was developed base d on the inversion of the cis-substituted alpha-cyclopropyl ester or a ldehyde anion to the trans ones. The method was applied to the synthes es of 3'-substituted CCG-I analogues.