APPLICATION OF CAPILLARY ELECTROPHORESIS TO THE QUALITY-CONTROL OF PHARMACEUTICAL FORMULATIONS - EFFECT OF AREA CORRECTION ON QUANTITATION OF ANTITUSSIVES

Authors
KORMAN M VINDEVOGEL J SANDRA P
Citation
M. Korman et al., APPLICATION OF CAPILLARY ELECTROPHORESIS TO THE QUALITY-CONTROL OF PHARMACEUTICAL FORMULATIONS - EFFECT OF AREA CORRECTION ON QUANTITATION OF ANTITUSSIVES, The Journal of microcolumn separations, 5(6), 1993, pp. 525-530
Citations number
9
Categorie Soggetti
Chemistry Analytical
Journal title
The Journal of microcolumn separations → ACNP
ISSN journal
10407685
Volume
5
Issue
6
Year of publication
1993
Pages
525 - 530
Database
ISI
SICI code
1040-7685(1993)5:6<525:AOCETT>2.0.ZU;2-G
Abstract
The application of capillary electrophoresis for assaying the drug con tent of pharmaceutical formulations has been studied. Correction of ar ea for migration times has been found useful in those cases where envi ronmental conditions lead to increased migration time variability. Fro m the results, the feasibility of single-point calibration with an ext ernal standard was shown and experimentally verified.