SYNTHESIS OF 2,4-DIHYDRO-4-(2-PHENYLETHYL)-5-(ISOMERIC PYRIDYL)-3H-1,2,4-TRIAZOLE-3-THIONES AND THEIR DERIVATIVES

Authors
IQBAL R ZAMANI K RAMA NH
Citation
R. Iqbal et al., SYNTHESIS OF 2,4-DIHYDRO-4-(2-PHENYLETHYL)-5-(ISOMERIC PYRIDYL)-3H-1,2,4-TRIAZOLE-3-THIONES AND THEIR DERIVATIVES, Turkish journal of chemistry, 20(4), 1996, pp. 295-301
Citations number
16
Categorie Soggetti
Chemistry,"Engineering, Chemical
Journal title
Turkish journal of chemistry → ACNP
ISSN journal
13000527
Volume
20
Issue
4
Year of publication
1996
Pages
295 - 301
Database
ISI
SICI code
1300-0527(1996)20:4<295:SO2P>2.0.ZU;2-K
Abstract
Intramolecular cyclization of the three isomeric 1,4-disubstituted thi osemicarbazides 3(a-c) in aqueous sodium hydroxide was attempted to ob tain 2,4-dihydro-4-(2-phenylethyl)-5-(isomeric pyridyl)-3H-1,2,4-triaz ole-3-thiones 4(a-c). Each of the three isolated triazoles was separat ely treated with benzyl chloride and with chloroacetic acid to furnish the corresponding benzylthio 5(a-c) and carboxymethylthio derivatives 6(a-c), respectively.